By A. Piney
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Extra info for Sternal Puncture. A Method of Clinical and Cytological Investigation
PERNICIOUS Α Ν Λ : Μ Ι Α (LATE STAGE IN TREATMENT) (a) Late megaloblast. (c) N o r m o b l a s t . (h) M y e l o c y t e . (d) Polychromatic normoblast. (e) Reticulocyte. B. —Numerous IDIOPATHIC HYPOCHROMIC ΑΝΛ:ΜΙΑ basophilic normoblasts, and hypochromic microcytosis. [To jace p. 36. THE ANÍÍ:MIAS 37 Lymphocytes . . . 1 - 3 per cent. Monocytes . . . i- 3 „ Haemohistioblasts . . o - 2 ,, Haemocytoblasts . . 2 - 5 ,, Promegaloblasts . . 5- 8 Basophilic megaloblasts . . 10-20 ,, Macronormoblasts (basophilic) .
O - 2 ,, Haemocytoblasts . . 2 - 5 ,, Promegaloblasts . . 5- 8 Basophilic megaloblasts . . 10-20 ,, Macronormoblasts (basophilic) . 20-40 ,, Normoblasts (late) . . 20-25 y y Megakaryocytes—moderate numbers at ends of film. Reticulocytes : up to 50 per cent, of the non-nucleated elements. Erythrocytes : still show megalocytosis, some hyperchromia, anisocytosis and poikilocytosis. In the late stages of treatment and in the stage of remission during continued treatment, the marrow film is rather uninteresting (Plate 9, A ) .
1 - 4 Pro-erythroblasts . . 25-34 Normoblasts . . . 20-30 Megaloblasts . . . 0 - 2 Megakaryocytes . . not increased Reticulocytes numerous. May be as high as 80 per cent, of the non-nucleated elements of the films. In many of the haemolytic anaemias, the anaemia may be macrocytic in type. In all the groups one or more such cases are described in the literature. Apart from the true megaloblastic reaction in Bartonella fever, however, the characteristic feature of these marrow films is the high percentage of pro-erythroblasts.